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Transfection Reagents Suitable for DNA and Protein Delivery

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Amerigo Scientific, a distributor focused on providing critical products and services to biomedical and life science communities, is pleased to announce the launch of its latest line of transfection reagents designed for the efficient delivery of DNA, siRNA, RNA, and proteins, powering up the transfection experiments for worldwide clients.

“We are excited to introduce our extensive transfection reagents to the research community,” said the business manager at Amerigo Scientific. “Our goal is to provide researchers with reliable and innovative tools that empower them to advance their research and make discoveries in the fields of molecular biology and cell biology.”

Transfection is a process of introducing nucleic acids or proteins into eukaryotic cells. This technique facilitates the study and understanding of the protein functions and gene regulations in cells and is used for clone generation, therapeutic protein production, and gene therapy application. Multiple methods of transfection can be divided into biological, chemical, and physical methods. In general, the ideal transfection method should be highly reproducible with high transfection efficiency, minimal cytotoxicity, and no major physiological alterations to the transfected cells.

The methods of transfecting genetic material into cells include chemical methods that can neutralize the negative charge of the DNA or RNA, physical methods that may cause temporary disruption of the plasma membrane to allow passage of genetic material into the cell, or biological methods that employ viruses as agents mediating nucleic acid transfer. According to whether foreign genes are integrated into the host cell genome, transfection methods can be divided into transient transfection and stable transfection. Transiently transfected gene is not integrated into the host genome and therefore the effect on target gene expression is time-limited. Transient transfection can be used to investigate the short-term impact of altered gene or protein expression. By contrast, in stable transfection, the transfected gene is either integrated into the genome of the host cell or maintained in episomal form.

Transfection is a crucial technique in molecular biology research, allowing researchers to introduce foreign genetic material into cells for a variety of applications, including gene expression studies,  therapeutic protein production, clone generation, and gene therapy. The choice of transfection reagents depends on the payload being delivered (DNA, RNA, or protein) and the type of cells being transfected.

Responding to the diverse transfection needs, Amerigo Scientific offers a wide suite of transfection reagents for DNA, siRNA, RNA, and protein delivery to best suit clients’ transfection experiments. The new transfection kits from Amerigo Scientific have been specifically formulated to ensure high transfection efficiency, minimal cytotoxicity, and consistent results across a wide range of cell types.

As one of Amerigo Scientific’s flagship transfection kits, the simple and rapid LipoMag kit has been widely used in all types of nucleic acids, including plasmid DNA, linearized DNA, siRNA, oligonucleotides, double-stranded RNA, mRNA, and shRNA. LipoMag kit can provide superior transgene expression levels and ensure successful transfections with minimal hassle, making it a convenient option for researchers.  

Moreover, Amerigo Scientific’s transfection reagents are available in a variety of formats, including lipid-based and polymer-based formulations, to suit different experimental requirements. Researchers interested in versatile transfection reagents are encouraged to explore the applications of these kits in basic research, drug discovery, and biotechnology.

About Amerigo Scientific

Amerigo Scientific, as a recognized distributor in the United States, collaborates closely with leading manufacturers worldwide and invites cooperation to all companies and institutions in the branch of reagents, kits, antibodies, and many other products for life science, biochemistry, and biotechnology. Its professional team is equipped with excellent technical support and thoughtful customer service. As most of its employees have earned a graduate (Ph.D. or M.S.) degree in life science, they can comprehend customers’ questions or concerns and are always ready to provide individualized customer service of high standards.