The long read sequencing market in North America is expected to grow from US$ 570.24 million in 2021 to US$ 2,254.97 million by 2028; it is estimated to grow at a CAGR of 21.7% from 2021 to 2028.
North America Long Read Sequencing Market Overview
Five years ago, genomic sequencing was primarily confined to research settings. Today, it has become an integral part of clinical practice, with projections indicating that over 60 million patients will have their genomic data sequenced within healthcare systems in the next five years. This rapid adoption has been fueled by significant government investments, exceeding $4 billion across at least 14 countries, aimed at integrating genomic medicine into healthcare. National genomic initiatives are overcoming implementation barriers and generating real-world evidence to support wider adoption, accelerating the growth of the North America Long Read Sequencing Market.
Market Dynamics in North America
North America dominates the long-read sequencing market, with the U.S. leading in market share, followed by Canada. Key growth drivers include:
- Rising demand for gene synthesis technologies from biopharmaceutical and biotechnology firms.
- Active R&D initiatives by academic and research institutions.
- Government and private-sector efforts to advance precision medicine.
- Substantial funding for genomic research from public and private entities.
- Increased adoption of advanced genomic technologies in healthcare.
The COVID-19 pandemic further accelerated market expansion, as genomic sequencing became crucial for tracking viral mutations and guiding public health responses.
Impact of COVID-19 on Market Growth
The U.S. was among the hardest-hit nations, leading to heightened demand for genomic surveillance. Initially lagging in sequencing efforts (ranking 43rd globally with only 3% of samples sequenced, per GISAID), the country has since ramped up its capabilities to monitor emerging variants.
Notable developments include:
- Canada’s $40 million Canadian COVID Genomics Network (CanCOGeN), a collaboration between Genome Canada, regional genome centers, public health labs, and industry partners.
- Pacific Biosciences and LabCorp’s partnership to sequence thousands of SARS-CoV-2 genomes using the Sequel II system.
These initiatives underscore the growing importance of long-read sequencing in pandemic response and broader clinical applications, positioning North America for sustained market leadership.
Future Outlook
With continued government support, technological advancements, and expanding clinical applications, the North America Long Read Sequencing Market is poised for exceptional growth. The ability to deliver highly accurate, comprehensive genomic data will further drive adoption across healthcare, biotechnology, and research sectors.
North America Long Read Sequencing Market Segmentation
North America Long Read Sequencing Market -By Technology
- Single-Molecule Real-Time Sequencing (SMRT)
- Nanopore Sequencing
- Loop Genomics Long-Read Sequencing
North America Long Read Sequencing Market -By Product
- Instruments
- Consumables
- Services
North America Long Read Sequencing Market -By Application
- Identification and fine mapping of structural variation
- Tandem Repeat Sequencing
- Pseudogene discrimination
- Resolving allele phasing
- Reproductive genomics
- Cancer
- Viral and Microbial Sequencing
- Others
North America Long Read Sequencing Market -By Workflow
- Pre-sequencing
- Sequencing
- Data Analysis
North America Long Read Sequencing Market -By End User
- Academic Research Institutes
- Hospitals and Clinics
- Pharma and Biotechnology Companies
North America Long Read Sequencing Market -By Country
- US
- Canada
- Mexico
North America Long Read Sequencing Market -Company Profiles
- Bionano Genomics
- F. HOFFMANN-LA ROCHE LTD.
- Illumina, Inc.
- Oxford Nanopore Technologies
- Pacific Biosciences of California, Inc.
- PerkinElmer, Inc.
- Quantapore, Inc.
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Author’s Bio:
Suryakant Gadekar
Senior Market Research Expert at Business Market Insights
